2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-173264
    SDH-IN-24
    		Inhibitor
    SDH-IN-24 (Compound 51) is an inhibitor of succinate dehydrogenase (SDH). The LC50 against the second-stage juveniles of Bursaphelenchus xylophilus (B. xylophilus) is 6.9 mg/L, and the IC50 for SDH is 15.0 μM. SDH-IN-24 exerts its nematicidal activity by inhibiting the activity of SDH to interfere with the energy metabolism of nematodes. Meanwhile, it inhibits the motility, feeding, and reproduction of nematodes, induces oxidative stress, reduces the protein content of nematodes, and impairs their antioxidant capacity. SDH-IN-24 can be used in the research related to anti-nematode fields.
    SDH-IN-24
  • HY-101397R
    Allopurinol riboside (Standard)
    		Inhibitor
    Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active.
    Allopurinol riboside (Standard)
  • HY-168931
    CCOE-5
    		Inhibitor
    CCOE-5 is a chalcone compound with antiplasmodial activity, showing an IC50 of 1.4 μg/mL against P. falciparum (3D7), and an IC50 of less than 5 μg/mL against P. falciparum (INDO). CCOE-5 holds promise for research in the field of anti-infective therapies.
    CCOE-5
  • HY-124232
    BTG 502
    		Inhibitor
    BTG 502 is an alkylamide insecticide. BTG 502 can reduce sodium current and antagonize the effect of bat toxin (BTX) on cockroach sodium channels.
    BTG 502
  • HY-B0273AR
    Sulfadiazine (sodium) (Standard)
    		Inhibitor
    Sulfadiazine (sodium) (Standard) is the analytical standard of Sulfadiazine (sodium). This product is intended for research and analytical applications. Sulfadiazine sodium is a sulfonamide?antibiotic with antimalarial activity. Sulfadiazine can be used for toxoplasmosis research.
    Sulfadiazine (sodium) (Standard)
  • HY-16973S5
    Fluralaner-d2
    		Inhibitor
    Fluralaner-d2 (A1443-d2) is deuterium labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
    Fluralaner-d<sub>2</sub>
  • HY-160675
    TCMDC-137332
    		Inhibitor
    TCMDC-137332 is a compound that exhibits antimalarial activity against Plasmodium falciparum with an IC50 value of 7 nM. TCMDC-137332 can be utilized for the research of malaria.
    TCMDC-137332
  • HY-163833
    MMV1634566
    		Inhibitor
    MMV1634566 is a potent antimalarial agent. MMV1634566 inhibits Plasmodium falciparum. MMV1634566 shows cytotoxicity.
    MMV1634566
  • HY-A0130R
    Sulfalene (Standard)
    		Inhibitor
    Sulfalene (Standard) is the analytical standard of Sulfalene. This product is intended for research and analytical applications. Sulfalene (Sulfametopyrazine) is an antimalarial agent. Sulfalene is also a long-acting sulfonamide antibacterial.
    Sulfalene (Standard)
  • HY-B1221R
    Flufenamic acid (Standard)
    		Inhibitor
    Flufenamic acid (Standard) is the analytical standard of Flufenamic acid. This product is intended for research and analytical applications. Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.
    Flufenamic acid (Standard)
  • HY-N15375
    Trichomycin B
    		Inhibitor
    Trichomycin B is a polyene macrolide antibiotic that can be isolated from the fermentation products of Streptomyces hachijoensis. Trichomycin B exhibits antibacterial activity against fungi, yeasts, and trichomonas. Trichomycin B can be used in research on antifungal and anti-trichomoniasis infection.
    Trichomycin B
  • HY-123305R
    5-Hydroxymebendazole (Standard)
    5-Hydroxymebendazole (Standard) is the analytical standard of 5-Hydroxymebendazole. This product is intended for research and analytical applications. 5-Hydroxymebendazole is the one metabolite of Benzimidazoles. Benzimidazoles are safe, broad-spectrum anthelmintic agents and are widely used for prevention and treatment of parasitic infections in food-producing animals.
    5-Hydroxymebendazole (Standard)
  • HY-126032
    Morantel
    		Inhibitor
    Morantel is an antinematodal agent. Morantel exhibits neuromuscular blocking properties.
    Morantel
  • HY-N14138
    Diolmycin A1
    		Inhibitor
    Diolmycin A1 is an antibiotic with anticoccidial activity.
    Diolmycin A1
  • HY-118865S
    Piperaquine-d6 tetraphosphate
    		Inhibitor
    Piperaquine-d6 (tetraphosphate) is the deuterium labeled Piperaquine tetraphosphate. Piperaquine tetraphosphate is a bisquinoline antimalarial agent. Piperaquine phosphate can be used in antimalarial research in combination with Artemisinin[1][2].
    Piperaquine-d<sub>6</sub> tetraphosphate
  • HY-172297
    Pyrazole N-Desmethyl sildenafil
    		Inhibitor
    Pyrazole N-Desmethyl sildenafil (Compound 10) is an analog of Sildenafil (HY-15025). Pyrazole N-Desmethyl sildenafil shows 16% inhibition on Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1) with 100 µM.
    Pyrazole N-Desmethyl sildenafil
  • HY-105117R
    Fantofarone (Standard)
    		Inhibitor
    Fantofarone (Standard) is the analytical standard of Fantofarone. This product is intended for research and analytical applications. Fantofarone is a highly potent Calcium Channel antagonist.
    Fantofarone (Standard)
  • HY-112542R
    Nemadectin (Standard)
    		Inhibitor
    Nemadectin (Standard) is the analytical standard of Nemadectin. This product is intended for research and analytical applications. Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity.
    Nemadectin (Standard)
  • HY-162899
    DXR-IN-3
    		Inhibitor
    DXR-IN-3 is a DXR inhibitor that specifically targets Toxoplasma gondii. DXR-IN-3 shows in vitro activity against the TgDXR enzyme, with an IC50 value of 0.62 μM and a Ki value of 0.19 μM. DXR-IN-3 can inhibit the proliferation of Toxoplasma, with an IC50 value of 5.46 μM.
    DXR-IN-3
  • HY-107814R
    Nicarbazin (Standard)
    		Inhibitor
    Nicarbazin (Standard) is the analytical standard of Nicarbazin. This product is intended for research and analytical applications. Nicarbazin is an effective anticoccidial agent for chickens.
    Nicarbazin (Standard)
Parasite Isoform Comparison

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